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GLP-1 Decoder

How to Get Tirzepatide: Brand vs Compounded Routes and Prices

To get tirzepatide you need a prescription. Then use insurance, or self-pay from $299 a month (LillyDirect: LillyDirect vial or KwikPen 2.5 mg).

Prescription
Required
Lowest self-pay
$299 a month
Telehealth from, all in
$373 a month
Shortage
Resolved

Zepbound in brief

How long it lasts in your body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

Half-life: 5 to 6 days. At 5.5 d, half is gone, and by the fifth half-life, 27.5 d, about 3% is left.

How much weight was lost in its main trial
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

In SURMOUNT-1 over 72 weeks, weight loss reached 20.9% of body weight, compared with 3.1% on placebo.

Prices over time
202420252026$1,086.37$0List priceSelf-pay

In US dollars, the monthly price points cover list price and self-pay offers, and each one is read from the maker's price page.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.

Every legit way to get tirzepatide, ranked

Ways to get it, cheapest first
RouteWho it is forWhat you pay
Mounjaro: Get it through your doctor using insurance and the savings cardCommercial insurance that covers itFor up to a 3-month fill, you may pay as little as $25
Zepbound: Get it through your doctor using insurance and the savings cardCommercial insurance that covers itFor up to a 3-month fill, you may pay as little as $25
Zepbound: LillyDirect: LillyDirect vial or KwikPen 2.5 mgAnyone with a prescription, no insurance needed$299 a month
Zepbound: TrumpRx listing (vial, starting)Self-pay only$299 a month
Zepbound: Walmart Pharmacy: LillyDirect self-pay (lowest dose)Cash at the pharmacy counter$299 a month
Telehealth: WeightWatchers Med+, Zepbound (self-pay)Online visit, medicine shipped$373 a month all in
Compounded copy: Mochi HealthNot FDA approved; ranked last for that reason$90 a month

Prices checked November 2026. Each price links to the page where it comes from.

Sources: pricinginfo.lilly.com, mounjaro.lilly.com, GoodRx, zepbound.lilly.com.

Who qualifies for it

Any GLP-1 sold in the US requires a prescription. A prescriber writes it for a use the label approves:

Source: FDA label (DailyMed).

Telehealth options compared

Telehealth programs for tirzepatide
ProgramMedicine optionMedicine priceMembershipAll in
WeightWatchers Med+Zepbound (self-pay)$299 a month$74 a month$373 a month
RoZepbound KwikPen, starting dose$299 a month$149 a month$448 a month
Hims & HersZepbound$1,899 a month$149 a month after first month$2,048 a month
Hims & HersMounjaro$1,899 a month$149 a month after first month$2,048 a month
Mochi HealthCompounded tirzepatide (not FDA approved)$90 a month$79 a month after free first month$169 a month
FoundCompounded GLP-1 plan (not FDA approved)$99 a month$169 a month cash$268 a month
Noom MedGLP-1Rx Plus Program (compounded GLP-1 with GIP, not FDA approved)once the first 4 weeks have passed, $299 a month, billed quarterlyNot listedIncluded

Each program's own pricing page lists the prices. No money comes to us from any of them.

Sources: weightwatchers.com, ro.co, hims.com, joinmochi.com.

Shortage status update

Tirzepatide: Shortage resolved. The FDA confirmed this on December 19, 2024.

Source: FDA.

Scam signals

Sources: pricinginfo.lilly.com, mounjaro.lilly.com, GoodRx, zepbound.lilly.com.

Find it in your state

More than anything else, Medicaid rules change which route you take. 10 state Medicaid programs cover GLP-1s used for weight loss today. Pick your state to check its drug list and prior authorization rules:

Sources: hims.com, noom.com, NovoCare.