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GLP-1 Decoder

Tirzepatide Insurance Coverage: Zepbound vs Mounjaro PA Rules

Insurance covers the tirzepatide brands differently: the diabetes brands are on most drug lists with prior authorization, while the weight-loss brands are covered only when your plan includes weight-loss drugs.

Plans tracked
18
Self-pay if denied
$299 a month

A quick look at Zepbound

How long it remains in the body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

The half-life is 5 to 6 days: 5.5 d leaves half behind, with about 3% still present at five half-lives (27.5 d).

The weight loss result from the main study
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

SURMOUNT-1 ran for 72 weeks, and weight loss reached 20.9% of body weight, while the placebo group recorded 3.1%.

Costs over time
202420252026$1,086.37$0List priceSelf-pay

Monthly US dollar prices include list prices and self-pay offers, each taken from the maker's price page.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.

Does insurance cover tirzepatide?

tirzepatide coverage by plan
PlanFor weight lossFor type 2 diabetesPrior authorization
MedicareBridge program onlyCovered by Part D plansRequired
MedicaidVaries by stateCoveredRequired
Cigna (Evernorth / Express Scripts)Plan dependentCovered on formularyRequired
Blue Cross Blue ShieldPlan dependentCovered on formularyRequired
Kaiser PermanentePlan dependentCovered on formularyRequired
AetnaEmployer optionCovered on formularyRequired
UnitedHealthcare (Optum Rx)Plan dependentCovered on formularyRequired
CVS CaremarkPlan sponsor choiceCovered on formularyRequired
Express ScriptsPlan sponsor choiceCovered on formularyRequired
Optum RxPlan sponsor choiceCovered on formularyRequired
HumanaBridge program onlyCovered by Part D plansRequired
TRICAREPrime and Select onlyCovered with PARequired
VA (Veterans Health Administration)Covered with criteriaCoveredRequired
GEHACovered with PACoveredRequired
Ambetter (Centene)ExcludedCovered on formularyRequired
ACA Marketplace plansRareCommonRequired
NavitusPlan sponsor choiceCovered on formularyNot listed
Amerigroup (Elevance Medicaid)Follows state MedicaidCovered with PARequired
Plan policies (18)

medicare.gov, KFF 1 2, aetna.com, static.cigna.com, uhcprovider.com, bluecrossma.org, healthy.kaiserpermanente.org, cvshealth.com, express-scripts.com, welcome.optumrx.com, humana.com, militaryrx.express-scripts.com, va.gov, geha.com, ambetterhealth.com, navitus.com, provider.amerigroup.com.

The published policy

Sources: humana.com, medicare.gov, CMS, aetna.com.

A checklist for prior authorization

Weight-loss prior authorization rules by plan
PlanWeight ruleLifestyle programTo keep coverage
AetnaThe baseline is BMI 30 or higher, or BMI 27 or higher with a weight-related condition6 months of a weight program first5% of baseline weight lost to renew
Cigna (Evernorth / Express Scripts)BMI 27 or higher with a weight-related conditionNot listed5% weight loss after 3 months
UnitedHealthcare (Optum Rx)BMI 27 or higher with a weight-related conditionNot listedNot listed
Blue Cross Blue ShieldWith BMI 35 or above, a weight-related condition is required (Horizon NJ)Not listedNot listed
VA (Veterans Health Administration)BMI 27 or higher with a weight-related conditionNot listedNot listed
Ambetter (Centene)BMI 27 or higher with established heart diseaseNot listedNot listed

Sources: aetna.com, static.cigna.com, uhcprovider.com, horizonblue.com.

The appeal, if you are denied

Denial reasons and fixes
Denial reasonWhat to send or ask
Criteria not metAsk your prescriber to resubmit it using your measured BMI and a chart list of all weight-related conditions.
The drug is not on the plan's listRequest a formulary exception, and ask which GLP-1 the plan prefers instead.
  1. Get the denial letter, which identifies the exact rule that was not met.
  2. With the appeal, your prescriber sends chart notes that address the rule.
  3. If the plan's appeal fails, ask for an external review by an independent reviewer.

Differences between states and plans

One state or employer plan from the same insurer may cover you while another does not.

Each state sets its own Medicaid rules. GLP-1s for weight loss have coverage now in 10 states: Delaware, Kansas, Michigan, Minnesota, Mississippi, Missouri, North Carolina, Tennessee, Virginia and Wisconsin. Compare every state side by side.

Sources: bluecrossma.org, horizonblue.com, info.caremark.com, healthy.kaiserpermanente.org.

Other choices if coverage says no

If coverage says no
MedicineLowest self-payManufacturer options when your plan offers no coverage
MounjaroNot listed$499 a month
Zepbound$299 a month$299 a month

Sources: pricinginfo.lilly.com, mounjaro.lilly.com, GoodRx, zepbound.lilly.com.