Tirzepatide Cost Without Insurance: Cash Prices by Route
Without insurance, the lowest tirzepatide self-pay price is $299 a month, for LillyDirect vial or KwikPen 2.5 mg. List prices run far higher.
- Lowest self-pay
- $299 a month
- Medicines compared
- 2
- Highest list price
- $1,112.16 per fill
The cost of tirzepatide without insurance for you varies with the medicine, strength, and seller. Self-pay programs offered by the manufacturer usually cost much less than the list price.
A quick look at Zepbound
A half-life of 5 to 6 days means half leaves after 5.5 d. About 3% remains following five half-lives (27.5 d).
At 72 weeks, SURMOUNT-1 showed 20.9% of body weight, compared with 3.1% on placebo.
In US dollars, monthly price points include list price and self-pay offers. Each comes from the maker's price page.
Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.
Cost of tirzepatide without insurance: the price table
Prices checked November 2026. Every price links to its source page.
Sources: pricinginfo.lilly.com, mounjaro.lilly.com, GoodRx, zepbound.lilly.com.
Costs by month and year
| Medicine | Lowest self-pay route | Per month | Per year (12 fills) |
|---|---|---|---|
 Zepbound | LillyDirect: LillyDirect vial or KwikPen 2.5 mg | $299 a month | $3,588 |
Sources: pricinginfo.lilly.com, mounjaro.lilly.com, GoodRx, zepbound.lilly.com.
Pages with prices for all medicines
Monthly costs and telehealth programs
Mochi Health program
$60 a month
Compounded semaglutide
Found
$99 a month
Compounded GLP-1 plan
Ro
$149 a month
Starting-dose Wegovy pill
Telehealth from Hims & Hers
$149 a month
Wegovy pill
Med+ from WeightWatchers
$149 a month
Foundayo pill (you pay on your own)
Prices shown here come from the pricing page for each program. We do not earn money from any of these programs.
Sources: ro.co, hims.com, henrymeds.com, noom.com.