Ozempic Skin Side Effects: Sagging, Rash, Itch
The Ozempic label does not list skin side effects as a side effect. What people mean by it: changes in how the skin looks or feels, such as rash, itching or tingling and burning.
- In the label
- Not listed
- Most common in the label
- Nausea 20.3%
Ozempic in brief
Half-life: about 1 week. After 7 d, half is gone; after five half-lives (35 d), about 3% is left.
SUSTAIN 1 ran 30 weeks in people with type 2 diabetes. Weight loss was 4.7 kg, against 1.2 kg on placebo.
In US dollars, monthly prices include the list price and self-pay offers. Each figure was taken from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
What the Ozempic label mentions instead
The Ozempic label does not list skin side effects. Of all the side effects it names, these five are the ones listed most often.
| Side effect | Placebo | Ozempic 0.5 mg | Ozempic 1 mg | More than placebo, 1 mg |
|---|---|---|---|---|
| Nausea | 6.1% | 15.8% | 20.3% | +14.2 points |
| Vomiting | 2.3% | 5% | 9.2% | +6.9 points |
| Diarrhea | 1.9% | 8.5% | 8.8% | +6.9 points |
| Abdominal pain | 4.6% | 7.3% | 5.7% | +1.1 points |
| Constipation | 1.5% | 5% | 3.1% | +1.6 points |
Source: Ozempic label (DailyMed).
Comparing skin side effects: Ozempic and other GLP-1s
Each label describes its own trials, and those trials used different groups of people. Use it as a rough guide.
| Medicine | Highest rate in the label | Dose group | Placebo | People in the trials |
|---|---|---|---|---|
 Saxenda | 3.2% | all doses | 0% | Children 12 and older with obesity |
 Wegovy | 2% | 2.4 mg | 1% | Adults with obesity or overweight (weight management) |
 Mounjaro | Listed, no rate given | – | – | – |
 Zepbound | Listed, no rate given | – | – | – |
 Foundayo | Listed, no rate given | – | – | – |
 Trulicity | Listed, no rate given | – | – | – |
| Byetta | Listed, no rate given | – | – | – |
| Ozempic | Not listed | – | – | – |
 Rybelsus | Not listed | – | – | – |
 Victoza | Not listed | – | – | – |
Sources: Wegovy label (DailyMed), Saxenda label (DailyMed).
Source: FDA label (DailyMed).