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GLP-1 Decoder

Zepbound Protein Calculator: Grams per Day by Weight and Goal

Zepbound protein: what to eat, what to limit, and why it matters on a GLP-1 medicine.

Active ingredient
tirzepatide
Manufacturer
Eli Lilly
How it is taken
Weekly injection (pen or vial)
FDA-approved for
Weight loss, Sleep apnea
Zepbound protein: a high-protein plate on a GLP-1

Zepbound, in short

How long it remains in the body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

Its half-life is 5 to 6 days: by 5.5 d half the dose has cleared, and five half-lives (27.5 d) leave about 3% behind.

How much weight was lost in its main trial
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

In the 72-week SURMOUNT-1 trial, 20.9% of body weight was lost, compared with 3.1% on placebo.

What it costs over time
202420252026$1,086.37$0List priceSelf-pay

Prices each month in US dollars: the list price and self-pay offers, with every figure read from the price page that the maker publishes.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.

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