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GLP-1 Decoder

Zepbound Foods to Avoid (and Why They Trigger Nausea and Reflux)

Zepbound foods to avoid: what to eat, what to limit, and why it matters on a GLP-1 medicine.

Active ingredient
tirzepatide
Manufacturer
Eli Lilly
How it is taken
Weekly injection (pen or vial)
FDA-approved for
Weight loss, Sleep apnea
Zepbound foods to avoid: a high-protein plate on a GLP-1

Zepbound in short

How long it remains in the body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

Its half-life is 5 to 6 days: by 5.5 d half is gone, and about 3% is left at five half-lives, or 27.5 d.

Main trial weight loss
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

In SURMOUNT-1 over 72 weeks, 20.9% of body weight compared with 3.1% on placebo.

Cost over time
202420252026$1,086.37$0List priceSelf-pay

In US dollars, monthly prices cover the list price and self-pay offers, and each figure comes from the maker's price page.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.