Zepbound and Exercise: Is It Safe? Label, Studies
Zepbound and exercise: what the label says, what doctors advise, and practical tips.
- Active ingredient
- tirzepatide
- Manufacturer
- Eli Lilly
- How it is taken
- Weekly injection (pen or vial)
- FDA-approved for
- Weight loss, Sleep apnea

A quick look at Zepbound
The half-life is 5 to 6 days: after 5.5 d, half is gone, and about 3% remains after five half-lives (27.5 d).
In SURMOUNT-1 over 72 weeks, people lost 20.9% of body weight, compared with 3.1% on placebo.
Prices each month, in US dollars: the list price, plus self-pay offers, all taken from the maker's price page.
Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.