Skip to content
GLP-1 Decoder

Zepbound and Keto: Is It Safe? Label, Studies

Zepbound and keto: what the label says, what doctors advise, and practical tips.

Active ingredient
tirzepatide
Manufacturer
Eli Lilly
How it is taken
Weekly injection (pen or vial)
FDA-approved for
Weight loss, Sleep apnea
Zepbound and keto: a morning walk on a quiet path

Zepbound in short

How long it lasts in your body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

Its half-life is 5 to 6 days: by 5.5 d, half is gone, and about 3% remains after five half-lives (27.5 d).

How much Weight was lost in its main trial
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

SURMOUNT-1 over 72 weeks: 20.9% of body weight, versus 3.1% on placebo.

How the price changes over time
202420252026$1,086.37$0List priceSelf-pay

In US dollars, the monthly price points cover the list price and self-pay offers; each figure comes from the maker's price page.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.