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GLP-1 Decoder

Ozempic Vision: How Common, How Long It Lasts, What Helps

The Ozempic label names retinopathy as a reported side effect but gives no trial rate for it.

In the label
Listed, no rate given
Label term
retinopathy

A quick look at Ozempic

Time in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

With a half-life of about 1 week, half disappears after 7 d; about 3% remains after five half-lives (35 d).

Main trial weight loss
Ozempic (SUSTAIN 1)4.7 kgPlacebo1.2 kg

In SUSTAIN 1, people with type 2 diabetes lost 4.7 kg over 30 weeks, compared with 1.2 kg on placebo.

Cost across time
202520262027$1,027.51$0List priceSelf-pay

In US dollars, monthly prices include the list price and self-pay offers. Each figure comes from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

What the Ozempic label lists instead

The Ozempic label provides no rate for vision changes. That label lists five side effects that occur most often, with rates for each.

Table 1. Adverse effects: Reactions seen in Placebo-Controlled Trials Reported in ≥5% of OZEMPIC-Treated Patients with Type 2 Diabetes Mellitus
Side effectPlaceboOzempic 0.5 mgOzempic 1 mgMore than placebo, 1 mg
Nausea6.1%15.8%20.3%+14.2 points
Vomiting2.3%5%9.2%+6.9 points
Diarrhea1.9%8.5%8.8%+6.9 points
Abdominal pain4.6%7.3%5.7%+1.1 points
Constipation1.5%5%3.1%+1.6 points

Source: Ozempic label (DailyMed).

Source: FDA label (DailyMed).

What the Ozempic label says

The label lists vision changes using these exact words:

“with type 2 diabetes and high cardiovascular risk, more events of diabetic retinopathy complications occurred in patients treated with OZEMPIC (3.0%) compared to placebo (1.8%).”

Source: FDA label (DailyMed).