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GLP-1 Decoder

Ozempic Menstrual: How Common, How Long It Lasts, What Helps

Period changes are not listed on the Ozempic label as a side effect. What people mean by it: changes in your period, such as timing or flow.

In the label
Not listed
Most common in the label
Nausea 20.3%

Ozempic: key facts

How long it remains in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

The half-life is about 1 week: half disappears after 7 d, while about 3% remains following five half-lives (35 d).

Weight loss in its main trial
Ozempic (SUSTAIN 1)4.7 kgPlacebo1.2 kg

In SUSTAIN 1, people with type 2 diabetes lost 4.7 kg over 30 weeks, compared with 1.2 kg on placebo.

Cost over time
202520262027$1,027.51$0List priceSelf-pay

Monthly prices in US dollars include list prices and self-pay offers, with each figure taken from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

What the Ozempic label lists instead of that

Period changes are not listed on the Ozempic label. The label lists these five side effects most often.

Table 1. Observed Adverse Reactions in Placebo-Controlled Trials Reported in ≥5% of OZEMPIC-Treated Patients with Type 2 Diabetes Mellitus
Side effectPlaceboOzempic 0.5 mgOzempic 1 mgMore than placebo, 1 mg
Nausea6.1%15.8%20.3%+14.2 points
Vomiting2.3%5%9.2%+6.9 points
Diarrhea1.9%8.5%8.8%+6.9 points
Abdominal pain4.6%7.3%5.7%+1.1 points
Constipation1.5%5%3.1%+1.6 points

For the source, see the Ozempic label (DailyMed).

Source: FDA label (DailyMed).