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GLP-1 Decoder

Does Blue Cross Blue Shield Cover Tirzepatide? Criteria, Copay

Blue Cross Blue Shield covers Zepbound for weight loss only when your employer or plan has added weight-loss drugs. Blue Cross Blue Shield covers Mounjaro for type 2 diabetes on its drug list, usually with prior authorization.

For weight loss
Plan dependent
For type 2 diabetes
Covered on formulary
Prior authorization
Required
Self-pay if denied
$299 a month

Zepbound: key facts

How long it remains in your body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

The drug has a half-life of 5 to 6 days. By 5.5 d, half has cleared; at five half-lives (27.5 d), about 3% remains.

Weight loss in its main trial
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

SURMOUNT-1 reported 20.9% for body weight over 72 weeks, versus 3.1% on placebo.

Costs over time
202420252026$1,086.37$0List priceSelf-pay

Monthly prices in US dollars include the list price and self-pay offers. Each comes from the maker's price page.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.

Is tirzepatide covered by Blue Cross Blue Shield?

Blue Cross Blue Shield and tirzepatide
MedicineApproved forStatusPrior authorization
MounjaroType 2 diabetes and heart riskCovered on formularyRequired
ZepboundWeight loss and sleep apneaPlan dependentRequired

Sources: pricinginfo.lilly.com, mounjaro.lilly.com, GoodRx, zepbound.lilly.com.

The policy as published

The federation of independent plans has the name Blue Cross Blue Shield

To read the policy text itself, visit bluecrossma.org

Sources: bluecrossma.org, horizonblue.com, info.caremark.com.

Prior authorization checklist

Source: horizonblue.com.

The appeal, if you are denied

Denial reasons and fixes
Denial reasonWhat to send or ask
The plan excludes weight-loss drugsThis is a plan design choice. Ask your employer's benefits team whether weight-loss drugs will be included when the plan renews. Blue Cross Massachusetts says its exclusion cannot be appealed.
Criteria not metHave your prescriber submit another request with your measured BMI and every weight-related condition listed in your chart
The drug is not on the plan's listRequest a formulary exception and ask which GLP-1 the plan favors as an alternative.
  1. The denial letter names the exact rule that had not been satisfied. Get it.
  2. Your prescriber files the appeal with chart notes that directly address that rule
  3. If the plan’s own appeal fails, request an external review from an independent reviewer

Source: bluecrossma.org.

Differences by State and plan

tirzepatide coverage at other plans
PlanFor weight lossPrior authorization
MedicareBridge program onlyRequired
MedicaidVaries by stateRequired
Cigna (Evernorth / Express Scripts)Plan dependentRequired
Kaiser PermanentePlan dependentRequired
AetnaEmployer optionRequired
UnitedHealthcare (Optum Rx)Plan dependentRequired
CVS CaremarkPlan sponsor choiceRequired
Express ScriptsPlan sponsor choiceRequired
Optum RxPlan sponsor choiceRequired
HumanaBridge program onlyRequired
TRICAREPrime and Select onlyRequired
VA (Veterans Health Administration)Covered with criteriaRequired
GEHACovered with PARequired
Ambetter (Centene)ExcludedRequired
ACA Marketplace plansRareRequired
NavitusPlan sponsor choiceNot listed
Amerigroup (Elevance Medicaid)Follows state MedicaidRequired

Each state sets its own Medicaid rules. Today, 10 states cover GLP-1s to help with weight loss. See every state.

If coverage says no, other routes

If coverage says no
MedicineLowest self-payIf your plan does not cover the drug, what does the manufacturer offer?
MounjaroNot listed$499 a month
Zepbound$299 a month$299 a month

Sources: pricinginfo.lilly.com, mounjaro.lilly.com, GoodRx, zepbound.lilly.com.