Semaglutide Alternatives: Every Option Compared on Results
7 other FDA-approved GLP-1 medicines share a use with Semaglutide: Mounjaro, Zepbound, Foundayo, Trulicity, Saxenda, Victoza and Byetta. Foundayo is a tablet, if you want to avoid needles. The lowest self-pay start among them is $149 per month for Foundayo.
- Same-use GLP-1 options
- 7
- Needle-free options
- Foundayo
- Lowest self-pay alternative
- $149 per month, Foundayo
Wegovy in brief
Its half-life is about 1 week. After 7 d, half is gone, and about 3% remains after five half-lives (35 d).
In STEP 1 at 68 weeks, people lost 14.9% of body weight, compared with 2.4% on placebo.
Monthly prices in US dollars include the list price and self-pay offers. Each comes from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Prescription alternatives to Semaglutide
| Medicine | Ingredient | How it is taken | Shared use |
|---|---|---|---|
 Mounjaro | tirzepatide | weekly injection | heart risk and type 2 diabetes |
 Trulicity | dulaglutide | weekly injection | heart risk and type 2 diabetes |
 Victoza | liraglutide | daily injection | heart risk and type 2 diabetes |
| Byetta | exenatide | twice-daily injection | type 2 diabetes |
Source: Eli Lilly.