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GLP-1 Decoder

New Weight Loss Drugs: Approved and Pipeline Options Compared

New weight loss drugs: what happened, what it means for patients, and where to read the record.

Half-life and weight loss overview

How long each drug remains in the body
Wegovy7 dOzempic7 dRybelsus7 dZepbound5.5 dMounjaro5 dTrulicity5 dFoundayo1.6 dSaxenda0.5 dVictoza0.5 dByetta0.1 d

Half-life, measured in days, tells you how long your body needs to remove half of a dose. Each FDA label includes this value in section 12.3.

Main trial results for weight loss by medicine
Zepbound20.9%Wegovy14.9%Foundayo11.1%Saxenda7.4%

A percentage of body weight. Compare each with the placebo on its own page, since trials, doses and lengths differ.

Sources (10)

The FDA label on DailyMed: 1 2 3 4 5 6 7 8 9 10.