Is Semaglutide the Same as Ozempic? Brand, Generic, Compounded

Side-by-side look at Ozempic and Semaglutide

Every row has the same ingredient. A brand's label is what decides the uses that are approved, the forms it comes in, and the price.

Every semaglutide brand, Ozempic first

Medicine	Ingredient	How it is taken	Approved for	Trial weight loss	Most common side effect	Self-pay from	List price
Ozempic	semaglutide	Weekly injection	Type 2 diabetes and heart risk, along with kidney disease in type 2 diabetes	Not listed	Nausea 20.3% vs 6.1% on placebo	$199 per month	$1,027.51 per pen
Wegovy	semaglutide	Weekly injection or daily tablet	Weight loss, heart risk and MASH liver disease	14.9%	Nausea 44% vs 16% on placebo	$149 per month	$1,349.02 per month
Rybelsus	semaglutide	Daily tablet	Type 2 diabetes and heart risk	Not listed	Nausea 20% vs 6% on placebo	Not listed	$1,027.51 per 30 tablets

Price and coverage: a comparison

Before and after savings, prices for each route

Medicine	How you pay	Price
Ozempic	List price before insurance	$1,027.51 per pen
Ozempic	Ozempic Savings Offer (insured)	starting at $25 per month, for terms of up to 3 months
Ozempic	Self-pay: Ozempic pill (from 1.5 mg)	$149 per month
Wegovy	List price before insurance	$1,349.02 per month
Wegovy	Wegovy Savings Offer (insured)	from $25 per month
Wegovy	Self-pay: Wegovy pill 1.5 mg	$149 per month
Wegovy	Medicare GLP-1 Bridge (Wegovy, eligible Part D)	$50 per month
Rybelsus	List price before insurance	$1,027.51 per 30 tablets
Rybelsus	RYBELSUS Savings Offer (insured)	for prices starting at $25, select a 1-, 2- or 3-month fill

Generic and compounded Semaglutide options

The injection shortage ended on February 21, 2025. Discontinuation is underway for older Rybelsus tablets.

Sources: FDA 1 2.

• Is There a Generic Ozempic? Status, Timeline, and What Counts as
• Compounded Semaglutide
• Compounded Ozempic