Ozempic Alternatives: Every Option Compared by Price and Results
6 other FDA-approved GLP-1 medicines share a use with Ozempic: Wegovy, Rybelsus, Mounjaro, Trulicity, Victoza and Byetta. Wegovy and Rybelsus are tablets, if you want to avoid needles. The lowest self-pay start among them is $149 per month for Wegovy.
- Same-use GLP-1 options
- 6
- Needle-free options
- Wegovy and Rybelsus
- Lowest self-pay alternative
- $149 per month, Wegovy
Ozempic in brief
The half-life is about 1 week. After 7 d, half remains; after five half-lives (35 d), about 3% is left.
In SUSTAIN 1, people with type 2 diabetes lost 4.7 kg over 30 weeks, compared with 1.2 kg on placebo.
Monthly prices in US dollars include the list price and self-pay offers. Each comes from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Prescription alternatives to Ozempic
| Medicine | Ingredient | How it is taken | Shared use | Trial weight loss | Self-pay from |
|---|---|---|---|---|---|
 Wegovy | semaglutide | weekly injection or daily tablet | heart risk | 14.9% | $149 per month |
 Rybelsus | semaglutide | daily tablet | heart risk and type 2 diabetes | Not listed | Not listed |
 Mounjaro | tirzepatide | weekly injection | heart risk and type 2 diabetes | Not listed | Not listed |
 Trulicity | dulaglutide | weekly injection | heart risk and type 2 diabetes | Not listed | Not listed |
 Victoza | liraglutide | daily injection | heart risk and type 2 diabetes | Not listed | Not listed |
| Byetta | exenatide | twice-daily injection | type 2 diabetes | Not listed | Not listed |
Sources: TrumpRx, FDA label (DailyMed).