GLP-1 vs Ozempic: Is It the Same Thing? Every GLP-1 Compared
Ozempic is one GLP-1 medicine; the group also includes Wegovy, Rybelsus, Mounjaro, Zepbound, Foundayo, Trulicity, Saxenda and Victoza. Ozempic is approved for heart risk; kidney disease with Type 2 diabetes; Type 2 diabetes, not for weight loss on its own.
- GLP-1 brands sold in the US
- 9
- Ozempic ingredient
- semaglutide
Ozempic in brief
Its half-life is about 1 week. Once 7 d pass, half is gone. Five half-lives (35 d) leave about 3% remaining.
In type 2 diabetes, the SUSTAIN 1 trial ran 30 weeks: 4.7 kg was lost, compared with 1.2 kg on placebo.
Monthly prices in US dollars cover list price and self-pay offers, and each one is read from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Ozempic and other GLP-1 brands
| Medicine | Ingredient | How it is taken | Approved for | Trial weight loss | Most common side effect | Self-pay from | List price |
|---|---|---|---|---|---|---|---|
 Ozempic | semaglutide | Weekly injection | Heart risk; kidney disease with Type 2 diabetes; Type 2 diabetes | Not listed | Nausea 20.3% vs 6.1% on placebo | $199 per month | $1,027.51 per pen |
 Wegovy | semaglutide | Weekly injection or daily tablet | Weight loss, heart risk and MASH liver disease | 14.9% | Nausea 44% vs 16% on placebo | $149 per month | $1,349.02 per month |
 Rybelsus | semaglutide | Daily tablet | Type 2 diabetes and heart risk | Not listed | Nausea 20% vs 6% on placebo | Not listed | $1,027.51 per 30 tablets |
 Mounjaro | tirzepatide | Weekly injection | Type 2 diabetes and heart risk | Not listed | Nausea 18% vs 4% on placebo | Not listed | $1,112.16 per fill |
 Zepbound | tirzepatide | Weekly injection | Weight loss and sleep apnea | 20.9% | Nausea 29% vs 8% on placebo | $299 per month | $499 to $1,086 per fill |
 Foundayo | orforglipron | Daily tablet | Weight loss | 11.1% | Nausea 35% vs 10% on placebo | $149 per month | $649 per month |
 Trulicity | dulaglutide | Weekly injection | Type 2 diabetes and heart risk | Not listed | Nausea 21.1% vs 5.3% on placebo | Not listed | $1,006.93 per fill |
 Saxenda | liraglutide | Daily injection | Weight loss | 7.4% | Nausea 39.3% vs 13.8% on placebo | Not listed | $1,349.02 per 5 pens |
 Victoza | liraglutide | Daily injection | Type 2 diabetes and heart risk | Not listed | Nausea 20% vs 5% on placebo | Not listed | $543.51 per 2 pens |