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GLP-1 Decoder

Who Makes Rybelsus? Novo Nordisk - and Why It Became Ozempic Pill

Who makes Rybelsus: the short answer first, then the details that matter.

Active ingredient
semaglutide
Manufacturer
Novo Nordisk
How it is taken
Daily pill
FDA-approved for
Type 2 diabetes, Heart risk
Who makes Rybelsus: pen injector cartridges on a pharmaceutical production line

Rybelsus: a quick look

How long it lasts in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

About 1 week is its half-life: by 7 d, half has gone, and about 3% remains after five half-lives (35 d).

Main trial weight loss
Rybelsus (PIONEER 1)3.7 kgPlacebo1.4 kg

In PIONEER 1, over 26 weeks people with type 2 diabetes lost 3.7 kg, compared with 1.4 kg on placebo.

Costs over time
20262027$1,027.51$0List priceSelf-pay

Monthly prices in US dollars cover the list price and self-pay offers, and each figure comes from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, Novo Nordisk pricing, Novo Nordisk.