Rybelsus Vial: What It Is, Price and How It Differs from the Pen
Rybelsus vial: which forms exist, which are FDA approved, and how they differ.
- Active ingredient
- semaglutide
- Manufacturer
- Novo Nordisk
- How it is taken
- Daily pill
- FDA-approved for
- Type 2 diabetes, Heart risk

Rybelsus in brief
Its half-life runs about 1 week. After 7 d, half is gone, and five half-lives (35 d) leave about 3% behind.
In PIONEER 1, people with type 2 diabetes lost 3.7 kg over 26 weeks, compared with 1.4 kg on placebo.
Prices by month in US dollars include the list price and self-pay offers. Each figure comes from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, Novo Nordisk pricing, Novo Nordisk.