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GLP-1 Decoder

Is There a Generic Rybelsus? Status, Timeline, and What Counts

Rybelsus generic: the short answer first, then the details that matter.

Active ingredient
semaglutide
Manufacturer
Novo Nordisk
How it is taken
Daily pill
FDA-approved for
Type 2 diabetes, Heart risk
Rybelsus generic: a prescription bag on a pharmacy counter

Rybelsus in short

How long it stays in your body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Its half-life is about 1 week: after 7 d half is gone, and after five half-lives (35 d) about 3% is left.

Weight lost in the main trial
Rybelsus (PIONEER 1)3.7 kgPlacebo1.4 kg

In PIONEER 1, over 26 weeks people with type 2 diabetes lost 3.7 kg, compared with 1.4 kg on placebo.

Price at different times
20262027$1,027.51$0List priceSelf-pay

Monthly prices in US dollars, shown as list price and self-pay offers, each taken from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, Novo Nordisk pricing, Novo Nordisk.