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GLP-1 Decoder

Wegovy Reddit: What r/Wegovy Reports vs. the STEP Trials

Wegovy reddit: the recurring themes in community discussion, set against the label.

Active ingredient
semaglutide
Manufacturer
Novo Nordisk
How it is taken
Weekly injection or daily pill
FDA-approved for
Weight loss, Heart risk, MASH liver disease

Key facts about Wegovy

How long it remains in your body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

The half-life is about 1 week. At 7 d, half is gone, and by five half-lives, which equal 35 d, about 3% remains.

How much weight was lost in the main trial
Wegovy (STEP 1)14.9%Placebo2.4%

In STEP 1 over 68 weeks, 14.9% of body weight was lost, against 2.4% on placebo.

Cost over time
202520262027$1,349.02$0List priceSelf-pay

Monthly prices in US dollars: the list price and self-pay offers, each taken from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.