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GLP-1 Decoder

Tirzepatide on Reddit: Recurring Questions

Tirzepatide reddit: the recurring themes in community discussion, set against the label.

Active ingredient
tirzepatide
Manufacturer
Eli Lilly

Zepbound in brief

How long it remains in the body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

Its half-life is 5 to 6 days. After 5.5 d, half is gone. About 3% remains after five half-lives (27.5 d).

Body weight lost in its main trial
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

The SURMOUNT-1 result after 72 weeks was 20.9% for body weight, versus 3.1% with placebo.

Changes in price
202420252026$1,086.37$0List priceSelf-pay

Monthly prices in US dollars include list price and self-pay offers. Each comes from the maker's price page.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.

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