A quick look at Trulicity

How long it remains in the body

Its half-life is about 5 days. After 5 d, half is gone, and after five half-lives (25 d) about 3% is left.

What makes it stall and what helps

See where you are in the dose steps. In the trials listed above, lower doses lose less weight. See which dose step you have reached.
Look back over the past month and count how many doses you missed or took late.
Write down what you eat and drink for a few days. When portions get smaller, calories from liquids and grazing add up.
Eat protein with every meal and keep up strength exercise, so most of what you lose is fat
Notice how sleep and stress affect your appetite.
Check with your pharmacist whether any other medicine you take can make you gain weight.
After months of stalled progress, one topic to raise with your prescriber is switching medicines, along with a check of your thyroid or blood sugar.