Ozempic vs Intermittent Fasting: Weight Loss, Side Effects
Ozempic is a GLP-1 medicine (weekly injection); intermittent fasting is an eating schedule, not a medicine. Ozempic is FDA approved for type 2 diabetes, heart risk, and kidney disease in people who have type 2 diabetes.
Ozempic in brief
Its half-life is about 1 week. After 7 d, half is gone, and about 3% remains after five half-lives (35 d).
In the 30-week SUSTAIN 1 trial of type 2 diabetes, people lost 4.7 kg, while the placebo group lost 1.2 kg.
The maker's price page lists monthly figures in US dollars for the list price and each self-pay offer.
Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.
Ozempic and Intermittent fasting: a side-by-side look
| Ozempic | Intermittent fasting | |
|---|---|---|
| Medicine | Ozempic | Intermittent fasting |
| Active ingredient | semaglutide | Not listed |
| Manufacturer | Novo Nordisk | Not listed |
| How it is taken | Weekly injection | Not listed |
| Approved for | Type 2 diabetes, heart risk, and kidney disease in people who have type 2 diabetes | Not listed |
| First FDA approval | 2017 | Not listed |
| Most common side effect | Nausea 20.3% vs 6.1% on placebo | Not listed |
| List price | $1,027.51 per pen | Not listed |
| Self-pay from | $199 per month | Not listed |
| FDA shortage | Resolved February 21, 2025 | Not listed |
| What it is | Not listed | An eating schedule, not a medicine |
Sources: FDA label, FDA label (DailyMed), Novo Nordisk pricing, TrumpRx.
Comparing prices and coverage
| Medicine | How you pay | Price |
|---|---|---|
| Ozempic | List price before insurance | $1,027.51 per pen |
| Ozempic | Ozempic Savings Offer (insured) | starting at $25 each month, for up to 3 months |
| Ozempic | Self-pay: Ozempic pill (from 1.5 mg) | $149 per month |
| Ozempic | With the Ozempic pen's self-pay introductory offer, the first 2 fills use the 0.25 mg and 0.5 mg doses | $199 per month |
| Ozempic | With self-pay, the Ozempic pen comes in doses of 0.25 mg and 0.5 mg, plus 1 mg | $349 per month |
| Ozempic | Self-pay: Ozempic pen 2 mg | $499 per month |
| Ozempic | Self-pay via TrumpRx | $199 per month |
Price checks done in November 2026: Novo Nordisk pricing, NovoCare, TrumpRx. Checked: NovoCare, TrumpRx.