Mounjaro for Type 1 Diabetes: Evidence, Eligibility
Mounjaro is not FDA approved for type 1 diabetes. It is approved for type 2 diabetes and heart risk.
- For type 1 diabetes
- Not an approved use
- Active ingredient
- tirzepatide
- How it is taken
- weekly injection
Mounjaro: a quick view
About 5 days is the half-life. At 5 d, half is gone; at 25 d, which is five half-lives, about 3% is left.
In SURPASS-1, people with type 2 diabetes lost 7.8 kg over 40 weeks, compared with 1 kg on placebo.
Monthly prices in US dollars show the list price and self-pay offers. Both come from the maker's price page.
Sources: FDA label (DailyMed), healthsystemtracker.org, pricinginfo.lilly.com.
Who qualifies?
| Source | Who qualifies |
|---|---|
| FDA label | Adults and children 10 and up with type 2 diabetes get lower blood sugar from this, when used with diet and exercise. |
| FDA label | For adults at high risk with type 2 diabetes, it lowers the chance of a heart attack, stroke, or heart-related death. |
Sources: FDA label (DailyMed).
Coverage for type 1 diabetes
| What changes | What the label says |
|---|---|
| Hypoglycemia When Combined with Insulin Secretagogues or Insulin | If taken with insulin or a sulfonylurea, this raises the chance of low blood sugar, so those doses may need lowering. |
| Taken with insulin or sulfonylureas | Low blood sugar becomes more likely if you use it with insulin or with a sulfonylurea, for example glipizide or glimepiride; your doctor may lower those amounts. |
From the FDA labels: FDA label at DailyMed.
Warnings from the label: FDA label (DailyMed).
Coverage for type 1 diabetes
- Mounjaro Coupon and Savings Card
- Mounjaro Price
- Cheapest Way to Get Mounjaro
- Mounjaro Cost Without Insurance
- Mounjaro Cost With Insurance
- Mounjaro Insurance Coverage
- Does Medicare Cover Mounjaro? Part D Rules, the Bridge, Copays
- Does BCBS Cover Mounjaro? Diabetes-Only Rules by Plan, Appeals
- Mounjaro Patient Assistance
Alternatives for type 1 diabetes
| Medicine | For type 1 diabetes | How it is taken |
|---|---|---|
| Not an approved use | weekly injection | |
| Not an approved use | weekly injection | |
| Not an approved use | weekly injection or daily tablet | |
| Not an approved use | daily tablet | |
| Not an approved use | weekly injection | |
| Not an approved use | daily tablet | |
| Not an approved use | weekly injection | |
| Not an approved use | daily injection | |
| Not an approved use | daily injection | |
| Byetta | Not an approved use | twice-daily injection |
Sources: FDA label (DailyMed).
Questions to ask your prescriber
- The label does not include type 1 diabetes.
- When I use my insulin, how will we deal with low blood sugar?
- Is off-label use covered by my plan?
See the full Mounjaro prescribing details on DailyMed.