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GLP-1 Decoder

Mounjaro for Type 1 Diabetes: Evidence, Eligibility

Mounjaro is not FDA approved for type 1 diabetes. It is approved for type 2 diabetes and heart risk.

For type 1 diabetes
Not an approved use
Active ingredient
tirzepatide
How it is taken
weekly injection

Mounjaro: a quick view

How long it remains in the body
100%50%25%0%05 d10 d15 d20 d25 d50%25%12.5%time after the dose

About 5 days is the half-life. At 5 d, half is gone; at 25 d, which is five half-lives, about 3% is left.

Weight loss in the main trial
Mounjaro (SURPASS-1)7.8 kgPlacebo1 kg

In SURPASS-1, people with type 2 diabetes lost 7.8 kg over 40 weeks, compared with 1 kg on placebo.

Price as time goes by
2026$1,112.16$0List priceSelf-pay

Monthly prices in US dollars show the list price and self-pay offers. Both come from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, pricinginfo.lilly.com.

Who qualifies?

Who qualifies for Mounjaro
SourceWho qualifies
FDA labelAdults and children 10 and up with type 2 diabetes get lower blood sugar from this, when used with diet and exercise.
FDA labelFor adults at high risk with type 2 diabetes, it lowers the chance of a heart attack, stroke, or heart-related death.

Sources: FDA label (DailyMed).

Coverage for type 1 diabetes

Mounjaro: what the label says about type 1 diabetes
What changesWhat the label says
Hypoglycemia When Combined with Insulin Secretagogues or InsulinIf taken with insulin or a sulfonylurea, this raises the chance of low blood sugar, so those doses may need lowering.
Taken with insulin or sulfonylureasLow blood sugar becomes more likely if you use it with insulin or with a sulfonylurea, for example glipizide or glimepiride; your doctor may lower those amounts.

From the FDA labels: FDA label at DailyMed.

Warnings from the label: FDA label (DailyMed).

Coverage for type 1 diabetes

Alternatives for type 1 diabetes

GLP-1 medicines and type 1 diabetes
MedicineFor type 1 diabetesHow it is taken
MounjaroNot an approved useweekly injection
OzempicNot an approved useweekly injection
WegovyNot an approved useweekly injection or daily tablet
RybelsusNot an approved usedaily tablet
ZepboundNot an approved useweekly injection
FoundayoNot an approved usedaily tablet
TrulicityNot an approved useweekly injection
SaxendaNot an approved usedaily injection
VictozaNot an approved usedaily injection
ByettaNot an approved usetwice-daily injection

Sources: FDA label (DailyMed).

Questions to ask your prescriber

See the full Mounjaro prescribing details on DailyMed.