Trulicity Before Surgery: When to Stop It
The Trulicity label warns that food can stay in the stomach longer during anesthesia or deep sedation. Tell the care team you take it before any procedure.
- Active ingredient
- dulaglutide
- How it is taken
- weekly injection
Trulicity: a quick look
Its half-life is about 5 days: after 5 d, half is gone, and after five half-lives (25 d), about 3% remains.
Sources: DailyMed FDA label.
Anesthesia and sedation: what the label covers
| Medicine | What the label says |
|---|---|
| Trulicity | Food may stay in the stomach longer, an important concern with anesthesia or deep sedation. Tell the care team before any procedure. |
FDA labels provide this information: FDA label (DailyMed).
How is it different before surgery?
| What changes | What the label says |
|---|---|
| Low Blood Sugar When Used with Insulin Secretagogues or Insulin | Taken alongside insulin or a sulfonylurea, it raises the risk of low blood sugar, and the doses may need to be lowered. |
| Severe Gastrointestinal Adverse Reactions | Side effects involving the stomach and intestines often occur and may be severe. Not recommended for people with severe gastroparesis. |
| Taken with oral medicines | Stomach emptying is delayed, which may change how the body absorbs other pills. |
FDA labels provide this information: FDA label (DailyMed).
From label warnings: FDA label (DailyMed).
Each GLP-1 label on surgery
| Medicine | What the label says | How it is taken |
|---|---|---|
| Trulicity | Label warning: tell the care team | weekly injection |
 Ozempic | Label warning: tell the care team | weekly injection |
 Wegovy | Label warning: tell the care team | weekly injection or daily tablet |
 Rybelsus | Label warning: tell the care team | daily tablet |
 Mounjaro | Label warning: tell the care team | weekly injection |
 Zepbound | Label warning: tell the care team | weekly injection |
 Foundayo | Label warning: tell the care team | daily tablet |
 Saxenda | Label warning: tell the care team | daily injection |
 Victoza | Label warning: tell the care team | daily injection |
| Byetta | Label warning: tell the care team | twice-daily injection |
Sources: DailyMed FDA label.
Questions to ask your prescriber
- Should I skip any dose before my procedure? If so, which dose would I skip?
- Do I need to be on a liquid diet the day before?
- Who on the surgical team needs to know?
Read the full prescribing details for Trulicity on DailyMed.