Trulicity Alternatives: Every GLP-1 and Non-GLP-1 Option Compared
6 other FDA-approved GLP-1 medicines share a use with Trulicity: Ozempic, Wegovy, Rybelsus, Mounjaro, Victoza and Byetta. Wegovy and Rybelsus are tablets, if you want to avoid needles. The lowest self-pay start among them is $149 per month for Wegovy.
- Same-use GLP-1 options
- 6
- Needle-free options
- Wegovy and Rybelsus
- Lowest self-pay alternative
- $149 per month, Wegovy
Trulicity: key facts
The half-life is about 5 days. After 5 d, half is gone. About 3% remains once five half-lives have passed (25 d).
Sources: FDA label (DailyMed).
Prescription alternatives to Trulicity
| Medicine | Ingredient | How it is taken | Shared use | Trial weight loss | Self-pay from |
|---|---|---|---|---|---|
 Ozempic | semaglutide | weekly injection | heart risk and type 2 diabetes | Not listed | $199 per month |
 Wegovy | semaglutide | weekly injection or daily tablet | heart risk | 14.9% | $149 per month |
 Rybelsus | semaglutide | daily tablet | heart risk and type 2 diabetes | Not listed | Not listed |
 Mounjaro | tirzepatide | weekly injection | heart risk and type 2 diabetes | Not listed | Not listed |
 Victoza | liraglutide | daily injection | heart risk and type 2 diabetes | Not listed | Not listed |
| Byetta | exenatide | twice-daily injection | type 2 diabetes | Not listed | Not listed |
Sources: TrumpRx, FDA label (DailyMed).