Stopping Liraglutide: Weight, Appetite
Agree a plan with your prescriber before you stop liraglutide. What you are trying to keep: in SCALE Obesity and Prediabetes, people on liraglutide 3.0 mg daily lost 7.4% on average over 56 weeks.
- Average loss, top dose
- 7.4%
- On placebo
- 3%
- Trial length
- 56 weeks
- Trial
- SCALE Obesity and Prediabetes
Saxenda in brief
Its half-life is about 13 hours: by 13 h half is gone, and at five half-lives (2.7 d) about 3% is left.
The result for SCALE Obesity and Prediabetes, 56 weeks, was 7.4% of body weight, versus 3% on placebo.
Sources: FDA label (DailyMed).
Liraglutide stopping: the numbers first
| Trial | Dose group | Average weight lost | Placebo or comparison | Weeks | Who was in it |
|---|---|---|---|---|---|
| SCALE Obesity and Prediabetes | Liraglutide 3.0 mg daily | 7.4% | 3% | 56 | Adults who had obesity or overweight, with no type 2 diabetes |
Source: SCALE Obesity and Prediabetes (FDA label (DailyMed)).
How to keep the weight off
- Speak with your prescriber first, so the plan includes follow-up visits and any other medicines.
- Stay with the eating habits you developed while on the drug: protein at every meal, smaller portions, and fewer sugary drinks.
- Stay active. Strength training helps you keep the muscle you already have.
- Set a schedule for weighing yourself, and agree ahead of time on what change should make you call your prescriber.
- Taking it for diabetes? Ask what the plan for your blood sugar will be once you stop.
How many people stopped during the trials
| Trial | Dose group | What happened | Drug | Placebo |
|---|---|---|---|---|
| SCALE Obesity and Prediabetes | All doses, label pool | Stopped for side effects | 9.8% | Not listed |
Source: SCALE Obesity and Prediabetes (FDA label (DailyMed)).