Skip to content
GLP-1 Decoder

What Ozempic Does: Blood Sugar, Weight, Heart

How Ozempic works: a plain explanation, with the facts from the prescribing information.

Active ingredient
semaglutide
Manufacturer
Novo Nordisk
How it is taken
Weekly injection
FDA-approved for
Type 2 diabetes, Heart risk, Kidney disease in type 2 diabetes
How Ozempic works: GLP-1 medicines as a pen, a pill and a vial

A quick look at Ozempic

How long it remains in the body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Its half-life is about 1 week: after 7 d half is gone, and after five half-lives (35 d) about 3% is left.

Weight lost in the main trial
Ozempic (SUSTAIN 1)4.7 kgPlacebo1.2 kg

In SUSTAIN 1, over 30 weeks with type 2 diabetes, 4.7 kg was lost against 1.2 kg on placebo.

Prices over time
202520262027$1,027.51$0List priceSelf-pay

Prices each month, in US dollars: the list price and self-pay offers, all found on the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.