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GLP-1 Decoder

Ozempic Benefits Beyond Weight: Heart, Kidney

Benefits of Ozempic: a plain explanation, with the facts from the prescribing information.

Active ingredient
semaglutide
Manufacturer
Novo Nordisk
How it is taken
Weekly injection
FDA-approved for
Type 2 diabetes, Heart risk, Kidney disease in type 2 diabetes
Benefits of Ozempic: GLP-1 medicines as a pen, a pill and a vial

Ozempic: the quick view

Time it remains in your body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Its half-life is about 1 week. After 7 d, half is gone, and after five half-lives (35 d), about 3% remains.

Amount of weight lost in its main trial
Ozempic (SUSTAIN 1)4.7 kgPlacebo1.2 kg

The 30-week SUSTAIN 1 trial in type 2 diabetes showed a loss of 4.7 kg, compared with 1.2 kg on placebo.

Cost over time
202520262027$1,027.51$0List priceSelf-pay

The maker's price page lists monthly price points in US dollars for both the list price and self-pay offers.

Sources: FDA label (DailyMed), healthsystemtracker.org, prnewswire.com 1 2.

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