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GLP-1 Decoder

Is There a Generic Tirzepatide? Names, Patents, Compounded

Tirzepatide generic: the short answer first, then the details that matter.

Active ingredient
tirzepatide
Manufacturer
Eli Lilly
Tirzepatide generic: a prescription bag on a pharmacy counter

A quick look at Zepbound

How long it lasts in your body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

Half-life: 5 to 6 days. At 5.5 d, half is gone, and about 3% remains after five half-lives (27.5 d).

The weight drop in its main trial
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

At 72 weeks in SURMOUNT-1, the result reached 20.9% of body weight, while placebo reached 3.1%.

How the price changes
202420252026$1,086.37$0List priceSelf-pay

Monthly prices in US dollars, shown as the list price and self-pay offers. Each figure comes from the maker's price page.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.