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GLP-1 Decoder

Tirzepatide vs Mounjaro: Same Drug? Brand, Zepbound

Mounjaro is a brand of tirzepatide, so the medicine inside is the same; Zepbound is the other tirzepatide brand. Mounjaro is approved for type 2 diabetes and heart risk.

Ingredient
tirzepatide
Manufacturer
Eli Lilly
Other tirzepatide brands
Zepbound
Lowest tirzepatide self-pay
$299 per month, Zepbound

Mounjaro and Zepbound at a glance

Half-life measured in days
Zepbound (5 to 6 days)5.5 dMounjaro (about 5 days)5 d

Sources: FDA label (DailyMed) 1 2.

Side-by-side comparison of Mounjaro and Tirzepatide

Every brand label gives approved uses, forms, and price for that brand.

Every tirzepatide brand, Mounjaro first
MedicineIngredientHow it is takenApproved forTrial weight lossMost common side effectSelf-pay fromList price
MounjarotirzepatideWeekly injectionType 2 diabetes and heart riskNot listedNausea 18% vs 4% on placeboNot listed$1,112.16 per fill
ZepboundtirzepatideWeekly injectionWeight loss and sleep apnea20.9%Nausea 29% vs 8% on placebo$299 per month$499 to $1,086 per fill

Sources are the FDA label (DailyMed) 1 2, pricinginfo.lilly.com 1 2, and TrumpRx.

Price and coverage compared

Cost by route: before savings, then after
MedicineHow you payPrice
MounjaroList price before insurance$1,112.16 per fill
MounjaroMounjaro Savings Card (insured)from $25 for up to a 3-month fill
MounjaroCommercial plan that does not cover it$499 per month
ZepboundList price before insurance$499 to $1,086 per fill
ZepboundZepbound Savings Program (insured)from $25 for up to a 3-month fill
ZepboundCommercial plan that does not cover it$299 per month
ZepboundSelf-pay: LillyDirect vial or KwikPen 2.5 mg$299 per month
ZepboundSelf-pay: LillyDirect vial or KwikPen 5 mg$399 per month
ZepboundSelf-pay through LillyDirect: 7.5 mg up to 15 mg (refill within 45 days)$449 per month
ZepboundSelf-pay: Standard pricing if you do not refill within 45 daysper month, $499 covers $7.5 mg, and $699 covers $10 to $15 mg
ZepboundSelf-pay via TrumpRx$299 per month
ZepboundMedicare GLP-1 Bridge (Zepbound KwikPen, eligible Part D)$50 per month
Prices checked November 2026 (7)

pricinginfo.lilly.com 1 2, mounjaro.lilly.com, zepbound.lilly.com, Eli Lilly, TrumpRx, CMS.

Generic and compounded Tirzepatide versions

Shortage resolved. FDA confirmed this on December 19, 2024.

Sources: FDA.