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GLP-1 Decoder

Protein on Rybelsus: How Much, Why It Matters, How to Hit It

Rybelsus protein: what to eat, what to limit, and why it matters on a GLP-1 medicine.

Active ingredient
semaglutide
Manufacturer
Novo Nordisk
How it is taken
Daily pill
FDA-approved for
Type 2 diabetes, Heart risk
Rybelsus protein: a high-protein plate on a GLP-1

Rybelsus in brief

How long it stays in your body
100%50%25%0%07 d14 d21 d28 d35 d50%25%12.5%time after the dose

Half-life: about 1 week. After 7 d, half is gone. About 3% remains after five half-lives (35 d).

Weight loss in the main trial
Rybelsus (PIONEER 1)3.7 kgPlacebo1.4 kg

In PIONEER 1, people with type 2 diabetes lost 3.7 kg over 26 weeks, against 1.4 kg on placebo.

Cost over time
20262027$1,027.51$0List priceSelf-pay

The maker's price page shows monthly price points in US dollars, including the list price and self-pay offers.

Sources: FDA label (DailyMed), healthsystemtracker.org, Novo Nordisk pricing, Novo Nordisk.