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GLP-1 Decoder

Petrelintide: Trial Results, Phase 3 Status

Petrelintide: where it is in development, what the trials show so far, and when it could reach patients.

Petrelintide at a glance

Weight loss seen in its main trial
Petrelintide10.7%Placebo1.7%

Weight loss at 42 weeks as a percent of body weight (ZUPREME-1, compared with 1.7% on placebo).

How long it stays inside the body
100%50%25%0%010 d20 d30 d40 d50 d50%25%12.5%time after the dose

Its half-life is about 10 days. After 10 d, half is gone, and about 3% remains after five half-lives, for a total of 50 d.

Sources: roche.com, europepmc.org.