Natural Saxenda Alternatives: Every Option Compared on Results
No supplement or diet is FDA approved to do what Saxenda does. The proven alternatives are other prescription GLP-1s such as Wegovy, Zepbound and Foundayo, plus eating and activity changes that help with any of them.
- Same-use GLP-1 options
- 3
- Needle-free options
- Wegovy and Foundayo
- Lowest self-pay alternative
- $149 per month, Wegovy
A quick look at Saxenda
The half-life is about 13 hours: after 13 h, half is gone, and about 3% remains after five half-lives, or 2.7 d in the body.
In the SCALE Obesity and Prediabetes, 56 weeks trial, weight loss was 7.4% of body weight, compared with 3% on placebo.
Sources: FDA label (DailyMed).
Alternatives to Saxenda that require a prescription
| Medicine | Ingredient | How it is taken | Shared use | Trial weight loss | Self-pay from |
|---|---|---|---|---|---|
 Wegovy | semaglutide | weekly injection or daily tablet | weight loss | 14.9% | $149 per month |
 Zepbound | tirzepatide | weekly injection | weight loss | 20.9% | $299 per month |
 Foundayo | orforglipron | daily tablet | weight loss | 11.1% | $149 per month |