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GLP-1 Decoder

How Mounjaro Works (and How Fast)

Mounjaro how it works: a plain explanation, with the facts from the prescribing information.

Active ingredient
tirzepatide
Manufacturer
Eli Lilly
How it is taken
Weekly injection
FDA-approved for
Type 2 diabetes, Heart risk
Mounjaro how it works: GLP-1 medicines as a pen, a pill and a vial

Mounjaro in short

How long does it stay in the body?
100%50%25%0%05 d10 d15 d20 d25 d50%25%12.5%time after the dose

Its half-life is about 5 days: after 5 d, half is gone, and about 3% remains after five half-lives (25 d).

Weight loss in its main trial
Mounjaro (SURPASS-1)7.8 kgPlacebo1 kg

In the 40-week SURPASS-1 trial of type 2 diabetes, 7.8 kg was lost, compared with 1 kg on placebo.

Costs over time
2026$1,112.16$0List priceSelf-pay

Monthly prices in US dollars include list prices and self-pay offers, each taken from the maker's price page.

Sources: FDA label (DailyMed), healthsystemtracker.org, pricinginfo.lilly.com.