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GLP-1 Decoder

How GLP-1 Drugs Work: Gut, Brain and Pancreas, Step by Step

How GLP-1 works: a plain explanation, with the facts from the prescribing information.

How GLP-1 works: GLP-1 medicines as a pen, a pill and a vial

Weight loss and half-life at a glance

How long each medicine stays in your body
Wegovy7 dOzempic7 dRybelsus7 dZepbound5.5 dMounjaro5 dTrulicity5 dFoundayo1.6 dSaxenda0.5 dVictoza0.5 dByetta0.1 d

Section 12.3 of each FDA label explains half-life in days, or how long your body takes to clear half a dose.

Weight loss in each medicine's main weight trial
Zepbound20.9%Wegovy14.9%Foundayo11.1%Saxenda7.4%

The percentage of body weight. The trials, doses, and lengths differ, so compare each result with the placebo on its page.

Sources (10)

FDA label (DailyMed) 1 2 3 4 5 6 7 8 9 10.