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GLP-1 Decoder

GLP-1 Agonists: How They Work, Every Drug, Side Effects

GLP-1 agonists: a plain explanation, with the facts from the prescribing information.

GLP-1 agonists: GLP-1 medicines as a pen, a pill and a vial

Weight loss and half-life overview

The time each stays in the body
Wegovy7 dOzempic7 dRybelsus7 dZepbound5.5 dMounjaro5 dTrulicity5 dFoundayo1.6 dSaxenda0.5 dVictoza0.5 dByetta0.1 d

In section 12.3 of each FDA label, half-life in days is the time the body needs to clear half of a dose.

Weight loss in the main weight trial for each medicine
Zepbound20.9%Wegovy14.9%Foundayo11.1%Saxenda7.4%

Percentage of body weight. Trials, doses and lengths differ, so on its page, compare each with its own placebo.

Sources (10)

FDA label information (DailyMed) 1 2 3 4 5 6 7 8 9 10.