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GLP-1 Decoder

Is There a Generic Zepbound? Status, Timeline, and What Counts

Zepbound generic: the short answer first, then the details that matter.

Active ingredient
tirzepatide
Manufacturer
Eli Lilly
How it is taken
Weekly injection (pen or vial)
FDA-approved for
Weight loss, Sleep apnea
Zepbound generic: a prescription bag on a pharmacy counter

Zepbound facts at a glance

How long it remains in your body
100%50%25%0%05.5 d11 d16.5 d22 d27.5 d50%25%12.5%time after the dose

The drug has a half-life of 5 to 6 days. After 5.5 d, half is gone. Following five half-lives (27.5 d), about 3% remains.

How much weight was lost in the main trial
SURMOUNT-1: 5 mg weekly15%SURMOUNT-1: 10 mg weekly19.5%SURMOUNT-1: 15 mg weekly20.9%Placebo3.1%

In SURMOUNT-1 over 72 weeks, people lost 20.9% of body weight, compared with 3.1% on placebo.

How the price changes
202420252026$1,086.37$0List priceSelf-pay

Monthly price points in US dollars: the list price and self-pay offers, with each figure taken from the price page the maker publishes.

Sources: FDA label (DailyMed), Eli Lilly 1 2, cnbc.com.